Michael K Riscoe Selected Research

4-thiouracil

10/2013

Substrate inhibition of uracil phosphoribosyltransferase by uracil can account for the uracil growth sensitivity of Leishmania donovani pyrimidine auxotrophs.

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Michael K Riscoe Research Topics

Disease

24	Malaria 01/2021 - 06/2007
8	Infections 01/2021 - 07/2012
5	Babesiosis (Piroplasmosis) 01/2021 - 01/2016
4	Toxoplasmosis 01/2020 - 09/2012
2	Parasitemia 01/2016 - 06/2015
2	Body Weight (Weight, Body) 01/2016 - 09/2015
1	Coccidiosis 01/2021
1	Latent Infection 01/2020
1	Cysts 01/2020
1	Tuberculosis (Tuberculoses) 01/2016
1	Hallucinations (Hallucination) 07/2014
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 07/2014
1	Hypersensitivity (Allergy) 10/2013
1	Calculi (Calculus) 07/2009
1	Nephrolithiasis 07/2009
1	Parasitic Diseases (Parasitic Disease) 04/2008
1	Multiple Sclerosis 11/2004
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 11/2004

Drug/Important Bio-Agent (IBA)

10	Pharmaceutical PreparationsIBA 01/2021 - 05/2009
8	QuinolonesIBA 01/2021 - 04/2008
7	Antimalarials (Antimalarial Agents)IBA 01/2021 - 05/2014
5	Atovaquone (Mepron)FDA Link 01/2021 - 05/2014
5	6- Chloro- 7- methoxy- 2- methyl- 3- (4- (4- (trifluoromethoxy)phenoxy)phenyl)quinolin- 4(1H)- oneIBA 12/2020 - 03/2013
4	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 01/2021 - 06/2015
4	ProdrugsIBA 01/2020 - 09/2015
3	Chloroquine (Aralen)FDA LinkGeneric 07/2014 - 07/2012
2	acridoneIBA 11/2020 - 11/2019
2	CarbonatesIBA 01/2020 - 02/2011
2	EstersIBA 01/2020 - 10/2017
2	ELQ-400IBA 11/2018 - 06/2015
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	Veterinary Drugs (Veterinary Drug)IBA 01/2021
1	pimagedine (aminoguanidine)IBA 01/2021
1	RobenidineIBA 01/2021
1	VaccinesIBA 11/2020
1	Mitochondrial DNA (mtDNA)IBA 01/2020
1	AcridonesIBA 11/2019
1	NADH DehydrogenaseIBA 01/2019
1	EnzymesIBA 01/2017
1	PolyaminesIBA 01/2017
1	Spermidine SynthaseIBA 01/2017
1	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 01/2017
1	Quinine (Quinson)FDA Link 01/2016
1	proguanil drug combination atovaquone (malarone)FDA Link 01/2016
1	Proguanil (Paludrine)FDA Link 01/2016
1	Drug CombinationsIBA 01/2016
1	Clindamycin (Cleocin)FDA LinkGeneric 01/2016
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2016
1	Mefloquine (Lariam)FDA LinkGeneric 07/2014
1	UracilIBA 10/2013
1	4-thiouracilIBA 10/2013
1	Fluorouracil (Carac)FDA LinkGeneric 10/2013
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 02/2011
1	Silicon Dioxide (Silica)FDA LinkGeneric 07/2009
1	SilicatesIBA 07/2009
1	alkoxyl radicalIBA 04/2008
1	Heme (Haem)IBA 02/2008
1	Coloring Agents (Dyes)IBA 06/2007
1	AntioxidantsIBA 11/2004
1	Thioctic Acid (Lipoic Acid)IBA 11/2004

Therapy/Procedure

5	Therapeutics 01/2021 - 04/2008
4	Oral Administration 11/2019 - 02/2011
1	Investigational Therapies (Experimental Therapy) 01/2021
1	Injections 08/2019